METABOLIC STUDIES WITH ETHANOLAMINE-1,2-C14
نویسندگان
چکیده
منابع مشابه
The metabolic fate of C14 labeled pentoses in man.
The role of pentoses in intermediary metabolism has received much attention within the past few years. The phosphate esters of D-ribose, D-ribulose and D-xylulose have been identified as key intermediates in the pentose phosphate pathway of glucose metabolism in both plant and mammalian tissue (1). More recently, another alternate pathway of glucose dissimilation, the uronic acid pathway, has b...
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The fate of hydrocortisone in man has been extensively studied (l-7) but the quantitative aspects of the transformation to its many metabolites in individual normal subjects leave much to be desired (8-16). This study reports the metabolism of an intravenous dose of hydrocortisone-4-Cl4 in five normal male subjects and of an oral dose in one of these subjects. The metabolites” cortol, /I-cortol...
متن کاملDifferentiation between vitamin B 12-deficient and folic acid-deficient megaloblastic anemias with C14-histidine.
.‘ 4EGALOBLASTIC ANEMIAS result from a relative or absolute defiI VI ciency of vitamin B12 or folic acid. Often it is difficult to make this etiologic differentiation, either from clinical observations or by use of routine hematologic procedures. Several methods which have been devised to evaluate folic acid deficiency have been reviewed recently.’ These include: therapeutic trial of “physiolog...
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The distribution of C(14) was studied in various parts of the rooster comb following treatment with testosterone. The value of gas-phase assay of C(14) in tissue has been demonstrated and the results compared with those of autoradiographic studies on the same tissue. The results of these experiments showed that androgen treatment significantly increases the rate of incorporation of C(14) in var...
متن کاملStudies on fluorinated pyrimidines. III. The metabolism of 5-fluorouracil-2-C14 and 5-fluoroorotic-2-C14 acid in vivo.
As one of the initial steps towards the determi nation of the metabolism and mechanism of action of fluorinated pyrimidines, 5-fluorouracil and 5fluoroorotic acid were labeled with radiocarbon in the 2-carbon atom. We have previously reported briefly that fluorouracil is incorporated, as such, into the combined nucleic acids of mouse liver, spleen, and Ehrlich ascites cells (9). The present rep...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1953
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)66145-9